Step 1: Preheat your oven to 350°F (175°C). Lightly grease a 9×5 inch loaf pan, or line a baking sheet with parchment paper and form the meatloaf into a loaf shape.
Step 2: In a medium skillet, heat 1 tablespoon of olive oil over medium heat. Add the finely chopped onion and bell pepper. Sauté for 5-7 minutes, or until softened and translucent. Let cool slightly.
Step 3: In a large mixing bowl, combine the ground beef, cooled sautéed vegetables, breadcrumbs, egg, milk, Worcestershire sauce, garlic powder, onion powder, dried oregano, salt, and black pepper. Mix gently with your hands until just combined, being careful not to overmix.
Step 4: Transfer the meat mixture to the prepared loaf pan, or form it into a loaf shape on a parchment-lined baking sheet. Gently press down to ensure it’s evenly distributed.
Step 5: In a small bowl, whisk together the ketchup, brown sugar, and apple cider vinegar until well combined to create the glaze.
Step 6: Pour about half of the glaze evenly over the top of the meatloaf. Reserve the remaining glaze for later.
Step 7: Bake for 45 minutes. Then, remove the meatloaf from the oven and spread the remaining glaze over the top. Return to the oven and bake for another 20-30 minutes, or until the internal temperature reaches 160°F (71°C).
Step 8: Once cooked, remove the meatloaf from the oven. Let it rest in the pan for 10-15 minutes before slicing. This allows the juices to redistribute, ensuring a moist meatloaf.
Step 9: Carefully remove the meatloaf from the pan, slice, and serve hot.